Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating

نویسندگان

  • Takashi Naohara
  • Hiromichi Aono
  • Tsunehiro Maehara
  • Hideyuki Hirazawa
  • Shinya Matsutomo
  • Yuji Watanabe
چکیده

To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Heat Generation and Transfer Behaviors of Ti-Coated Carbon Steel Rod Adaptable for Ablation Therapy of Oral Cancer

For the purpose of developing a novel ablation therapy for oral cancer, the heat generation and transfer properties of a Ti-coated carbon steel rod with 20-mm length and 1.8-mm outer diameter were investigated by means of a high-frequency induction technique at 300 kHz. The heat generation measurement performed using water (15 mL) revealed that the difference of the inclination angles (θ = 0°, ...

متن کامل

Evaluation of a Novel Thermobrachytherapy Seed for Concurrent Administration of Brachytherapy and Magnetically Mediated Hyperthermia in Treatment of Solid Tumors

Concurrent hyperthermia and radiation therapy in treatment of cancer show a strong evidence of a synergistic enhancement. We designed a new self-regulating Thermo-Brachytherapy seed, which serves as a source of both radiation and heat for concurrent administration of brachytherapy and hyperthermia. The Thermo-Brachytherapy seed has a core of ferromagnetic material which produces heat when subje...

متن کامل

Magnetization Measurements of PdNi, PdCo and ZCuNi Ferromagnetic Thermoseeds

High quality heating device made of ferromagnetic alloy (thermal seed) was developed for hyperthermia treatment of cancer. Ferromagnetic seeds of PdNi, PdCo and CuNi are prepared by induction furnace and subsequent heat treatment. Magnetic induction and hysteresis loops are measured as functions of temperature. The power dissipated from each seed was calculated from the area enclosed by the hys...

متن کامل

Irreversible electroporation of the porcine kidney: Temperature development and distribution.

OBJECTIVE Although tissue ablation by irreversible electroporation (IRE) has been characterized as nonthermal, the application of frequent repetitive high-intensity electric pulses has the potential of substantially heating the targeted tissue and causing thermal damage. This study evaluates the risk of possible thermal damage by measuring temperature development and distribution during IRE of ...

متن کامل

Anesthetic considerations in patients undergoing percutaneous radiofrequency interstitial tissue ablation.

Radiofrequency (RF) interstitial tissue ablation is a new, minimally invasive procedure for patients with liver cancer who are not candidates for conventional therapy. The percutaneous RF ablation therapy involves placing a needle electrode under ultrasound guidance into a selected portion of the tumor and heating the tissue between 90 degrees C and 100 degrees C. The ablation procedure can be ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2012